Gentse memoriedagen: 25-26-27-28 mei.
نویسندگان
چکیده
منابع مشابه
Npgrj_NCHEMBIO_128 26..28
Fluorination has gained an increasingly important role in drug discovery and development. Here we describe a versatile strategy that combines cytochrome P450–catalyzed oxygenation with deoxofluorination to achieve monoand polyfluorination of nonreactive sites in a variety of organic scaffolds. This procedure was applied for the rapid identification of fluorinated drug derivatives with enhanced ...
متن کاملNpgRj_Nn_1592 26..27
Voluntary actions typically produce suppression of afferent sensation from the moving body part. We used transcranial magnetic stimulation to delay the output of motor commands from the motor cortex during voluntary movement. We show attenuation of sensation during this delay, in the absence of movement. We conclude that sensory suppression mainly relies on central signals related to the prepar...
متن کامل[ 25 ] Purification and Analysis of Recombinant 11 S Activators of the 20 S Proteasome : Trypanosoma brucei PA 26 and Human PA 28 , PA 28 , and PA 28
Proteasomes perform the bulk of nonlysosomal degradation of aberrant, damaged, misfolded, and naturally short‐lived regulatory proteins in eukaryotic cells. They are 700‐kDa assemblies whose hollow architecture sequesters the proteolytic sites inside a central chamber, thereby ensuring that the activity of isolated proteasomes is repressed. In vivo, proteasomes are activated by protein complexe...
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ژورنال
عنوان ژورنال: Ghendtsche Tydinghen
سال: 1970
ISSN: 1783-9033
DOI: 10.21825/gt.v31i4.6086